Understanding the ZEBRA Mnemonic: A Root-Cause Approach to Health
- evacupuncturist
- Aug 11
- 2 min read
Updated: Sep 3
Longtime followers know the ZEBRA mnemonic well. It stands for a comprehensive approach to addressing mood and sleep issues. This method emphasizes self-care, hormone balance, and exercise, focusing on nutrient density, robust digestion, and biochemistry. Let's break it down!
The ZEBRA Components
Zinc and other minerals are crucial for neurotransmitter and mitochondrial function. Unfortunately, these are often missing in U.S. diets.
Essential fatty acids play a vital role in overall health.
B vitamins are usually produced by "gut buddies" in a healthy gut or absorbed in the stomach.
Rebalancing gut flora is essential for maintaining a healthy microbiome.
Amino acids are best measured in plasma rather than urine.
Self-Care: Take Care of Yourself!
Self-care is not just a buzzword; it’s a necessity. Taking care of your mental and physical health can significantly impact your overall well-being.
Hormones Matter
Hormonal balance is crucial for mood regulation and cognitive function. When hormones are out of whack, it can lead to a host of issues, including anxiety and depression.
Exercise: Move to Improve
Exercise is a powerful tool for enhancing mood and cognitive function. It releases endorphins, which can help alleviate feelings of sadness and anxiety.
How to Assess Your Current Health Status
So, how do you know where you stand? Channeling Chris Kresser, I say: "Test, don't guess." Your GP or other healthcare provider may not provide the insights you need unless you have a standout case.
DIY Testing Options
For those in states like New York, New Jersey, Rhode Island, and Maryland, DIY testing might be limited due to hospital lobbyists. However, there are still affordable and reliable options available. Sending kits to a work address or a relative’s home often works well.
Desired Levels of Nutrients
Here’s a quick reference table for desired nutrient levels:
| Zinc (serum); Zinc (RBC) | 90-110; 9.0-14.7 (mg/L) | Oysters, organ meats, green pumpkin seeds | Impaired taste/smell, slow healing | Rupa Health: blood, hair |
| Copper | 90-110 | Beef liver, oysters, baking chocolate | Copper deficiency is rare; copper excess, less so: GI, neurological, hematological | Rupa Health: blood, hair |
| Magnesium (RBC) | 5.2-6.5 | Dark leafy greens, oatmeal | Muscle spasms, depression | Rupa Health: blood, hair |
Testing for Gut Flora Balance
To assess your gut flora balance, consider these options:
GI Effects
Testing for Amino Acid Sufficiency
To check your amino acid levels, you can use:
Instead of doing these tests individually, consider getting them all in one place. NutrEval ($439) is a great option, although it doesn't include iodine or hormones.
Conclusion
Understanding the ZEBRA mnemonic and how to assess your health can empower you to take charge of your well-being. By focusing on nutrient density, gut health, and hormonal balance, you can pave the way for a healthier, happier life. Remember, testing is key! So, let’s get started on this journey together!



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